Mechanical signals and IGF-I gene splici
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Umber Cheema; Robert Brown; Vivek Mudera; Shi Yu Yang; Gus McGrouther; Geoffrey
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Article
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2004
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John Wiley and Sons
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English
β 239 KB
## Abstract It has been shown that the insulinβlike growth factor (IGFβI) gene is spliced in response to mechanical signals producing forms of IGFβI which have different actions. In order to study how mechanical signals influence this gene splicing in developing muscle, C~2~C~12~ cells were grown i