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Palmitate-induced PTP1B expression is mediated by ceramide-JNK and nuclear factor κB (NF-κB) activation

✍ Scribed by Narges MohammadTaghvaei; Gholamreza Taheripak; Mohammad Taghikhani; Reza Meshkani


Book ID
116354912
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
786 KB
Volume
24
Category
Article
ISSN
0898-6568

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Atypical PKC ζ is activated by ceramide,
✍ YongMing Wang; M. Lamar Seibenhener; Michel L. Vandenplas; Marie W. Wooten 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 1 views

Both protein kinase C (PKC) and ceramide play a critical role in cell signaling, but the relationship between PKC and ceramide is unclear. Low concentrations of ceramide were observed to transiently stimulate PKC activity in vitro and in vivo, whereas high doses of ceramide lead to inhibition of PKC