In the ®rst trimester of pregnancy the biochemical markers free b-hCG and pregnancy associated plasma protein-A (PAPP-A) are used for the prenatal screening of trisomy 21, either alone or in combination with nuchal translucency (NT) thickness. In this study, I have analysed the distribution of these
✦ LIBER ✦
Pallister–Killian syndrome presenting through nuchal translucency screening for trisomy 21
✍ Scribed by K. Langford; S. Hodgson; M. Seller; D. Maxwell
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 69 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0197-3851
No coin nor oath required. For personal study only.
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In a study of 2923 normal pregnancies and 203 pregnancies affected by trisomy 21 we have shown a signi®cant difference in the median MoM of the markers: fetal nuchal translucency, maternal serum free b-hCG and PAPP-A in the presence of a female fetus compared with a male fetus. For maternal serum fr