Pallidal stimulation reduces treatment-induced dyskinesias in “minimal-change” multiple system atrophy
✍ Scribed by Yue Huang; Raymond Garrick; Raymond Cook; Dudley O'Sullivan; John Morris; Glenda M. Halliday
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 197 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
Deep brain stimulation therapy is increasingly gaining acceptance in the management of levodopa‐induced dyskinesia and fluctuations in idiopathic Parkinson's disease. It is generally not recommended for the other forms of parkinsonism such as progressive supranuclear palsy or multiple system atrophy where the response to levodopa is usually poor and disease progression more rapid, making any benefit short‐lived. Here, we present an autopsy‐confirmed case of “minimal‐change” multiple system atrophy in whom pallidal stimulation surgery was effective in abolishing severe levodopa‐induced dyskinesia. © 2005 Movement Disorder Society