## Abstract We investigated the control of movement in 12 patients with Parkinson's disease (PD) after they received surgically implanted highβfrequency stimulating electrodes in the subthalamic nucleus (STN). The experiment studied ankle strength, movement velocity, and the associated electromyogr
Pallidal stimulation: Effect of pattern and rate on bradykinesia in the non-human primate model of Parkinson's disease
β Scribed by Kenneth B. Baker; Jianyu Zhang; Jerrold L. Vitek
- Book ID
- 113616855
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 238 KB
- Volume
- 231
- Category
- Article
- ISSN
- 0014-4886
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Cardinal symptoms of Parkinson's disease (PD) respond well to treatment with levodopa and deep brain stimulation (DBS) of the subthalamic nucleus (STN). However, it has remained unclear whether levodopa and STN-DBS have differential effects on bradykinesia. We investigated 8 PD-patients with STN-ele
## Abstract Deep brain stimulation (DBS) is an effective treatment for selected patients with disabling Parkinson's disease (PD). The two main targets are the subthalamic nucleus (STN) and the globus pallidus internus (GPi), although it has not been established whether stimulation at one target is