Palliative treatment of neuroendocrine tumors
β Scribed by Dr. J. Gregory McKinnon
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 704 KB
- Volume
- 9
- Category
- Article
- ISSN
- 8756-0437
No coin nor oath required. For personal study only.
β¦ Synopsis
Effective palliation of patients with incurable neuroendocrine tumors requires both control of hormonal overproduction symptoms as well as control of tumor growth. Several important advances have been made in recent years toward these two goals. Octreotide and omeprazole have both been extremely effective in ameliorating hormonal symptoms of carcinoids, islet cell tumors and medullary thyroid carcinoma. Newer cytotoxic chemotherapy regimens and interferon have increased response rates over traditional therapy. More aggressive surgical extirpation of metastatic disease has also been beneficial.
π SIMILAR VOLUMES
The aggressiveness of poorly-differentiated neuroendocrine tumors is similar to small-cell lung cancer within a median survival of 6 months without treatment. Most patients have metastatic disease and poor condition at the time of diagnosis, and cannot be approached surgically with curative intent.
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