Palladium(0)-catalyzed allylation of uracils and 2-thiouracils drastic effect of an aqueous reaction medium on the regioselectivity

Palladium(0)-catalyzed substitution of a

Palladium(0)-catalyzed substitution of allylic substrates in an aqueous-organic medium. Influence of various parameters on the selectivity of the reaction

✍ Silvana Sigismondi; Denis Sinou 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 665 KB

The regioselectivity of the reaction of ethyl acetoacetate on allylic carbonate in the presence of a catalyst prepared from Pd(OAc), and P(C,H,-m-SO,Na), (or tppts) is not affected by the ratio Pd(OAc),/tppts, the nature of the nitrile, the relative amounts of water and nitrile or the temperature of