Palladium-Catalyzed α-Arylation of Ketones
✍ Scribed by Palucki, Michael; Buchwald, Stephen L.
- Book ID
- 120399808
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 92 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Palladium-Catalyzed Intramolecular ct-Arylation of A1iphatic Ketones ResearchFoundationItsuuLaboratory 2-28-10Tamagaw~Setagaya-ku, Tokyo158,Japan Cyclizstion reaction of5 -10 10 mol%ofPdCl(Ph3P) in the presence of 3 q of C~COĩnhotTHPortoluene afforded bridged orSPUO mrpmmdsfl -~c in tl~to mod~t
The generation of quatenary chiral centers through catalytic asymmetric alkylation of ketone enolates has been the subject of investigation in recent years. [1] The palladiumcatalyzed asymmetric allylic alkylation (AAA) of prochiral nucleophiles represents one such strategy for the creation of quate