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Palladium-catalyzed three component coupling on solid support

✍ Scribed by Yao Wang; Tai-Nang Huang

Book ID
104261985
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
179 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

Three component coupling of aryl halides, dienes and amines catalyzed by palladium, an efficient method of making aryl-substituted allylic amines, was successfully adapted to solid-phase synthesis. Amines were chosen to attach to a solid support, and reacted with a variety of aryl halides and dienes to give coupled products in good results.

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