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Palladium-catalyzed synthesis of symmetrical urea derivatives by oxidative carbonylation of primary amines in carbon dioxide medium

✍ Scribed by Nicola Della Ca’; Paolo Bottarelli; Angela Dibenedetto; Michele Aresta; Bartolo Gabriele; Giuseppe Salerno; Mirco Costa


Book ID
113687014
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
527 KB
Volume
282
Category
Article
ISSN
0021-9517

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## Abstract The oxidative carbonylation of readily available (__Z__)‐(2‐en‐4‐ynyl)amines, catalyzed by the PdI~2~‐KI system, selectively afforded in satisfactory yields (40–95 %) either pyrrole‐2‐acetic ester or (pyridine‐2‐one)‐3‐acetic amide derivatives, depending on the susbtitution pattern of t