Palladium-catalyzed synthesis of new unsaturated exo-enol lactones with potential biological activity.
✍ Scribed by Didier Bouyssi; Jacques Gore; Geneviève Balme; Dominique Louis; Jean Wallach
- Book ID
- 108382174
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 145 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
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## Abstract magnified image Reaction of visnaginone which derived from the naturally occurring compound “visnagine”, with allyl bromide gave __O__‐allyl visnaginone **1**, which underwent Claisen rearrangement to yield 7‐allylbenzofuran **2** derivative. Vilsmeier Haack formylation of **2** afford
Enol acetates derived from saturated ketones are converted to a,&unsaturated ketones by heating with ally1 methyl carbonate in MeCN by bimetallic catalysis of palladiumphosphine complex and tin methoxide. Conversion of saturated ketones to corresponding a,&unsaturated ketones is an important synthet