Palladium-Catalyzed Synthesis of N-Aryl-2-benzylindolines via Tandem Arylation of 2-Allylaniline: Control of Selectivity Through in situ Catalyst Modification.

Palladium(II) and bidentate phosphine-ca

Palladium(II) and bidentate phosphine-catalyzed selective synthesis of N-aryl-2-pyrrolidinones via cyclocarbonylative coupling of 2-aminophenol and 2-aminothiophenol

✍ Luigia Longo; Giuseppe Mele; Giuseppe Ciccarella; Vito Sgobba; Bassam El Ali; Gi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 2 views

## Abstract The inter‐ and intra‐molecular regioselective cyclocarbonylative coupling of 2‐aminophenol (**1a**) and 2‐aminothiophenol (**1b**) with various allylhalides was achieved in the presence of a catalytic amount of palladium acetate and 1,4‐bis(diphenylphosphino)butane to afford __N__‐aryl‐