Palladium-catalyzed Suzuki reaction using 1,3-dialkylbenzimidazol-2-ylidene ligands in aqueous media

✍ Scribed by İsmail Özdemir; Yetkin Gök; Nevin Gürbüz; Engin Çetinkaya; Bekir Çetinkaya

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 92 KB
• Volume: 15
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20034

✦ Synopsis

Abstract

From readily available starting compounds, six functionalized 1,3‐dialkylbenzimidazolium salts (2a–c and 4a–c) have been prepared and characterized by conventional spectroscopic methods and elemental analyses. A highly effective, easy to handle, and environmentally benign process for palladium‐mediated Suzuki cross‐coupling was developed. The in situ prepared three‐component systems Pd(OAc)~2~/1,3‐dialkylbenzimidazolium chlorides and Cs~2~CO~3~ catalyze quantitatively the Suzuki cross‐coupling of deactivated aryl chlorides. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:419–423, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20034