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Palladium-Catalyzed Selective Acyloxylation Using Sodium Perborate as Oxidant

✍ Scribed by Pilarski, Lukasz T.; Janson, Pär G.; Szabó, Kálmán J.


Book ID
111674130
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
813 KB
Volume
76
Category
Article
ISSN
0022-3263

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A chelation-assisted palladium-catalyzed acyloxylation of the sp 3 C-H bond of benzyl by carboxylic acid is described, which employs PhI(OAc) 2 as a stoichiometric oxidant. The procedure tolerates a series of functional groups, such as methoxyl, chloro, bromo, iodo, vinyl, formyl, phenolic hydroxyl,