✦ LIBER ✦
Palladium-Catalyzed Intramolecular Coupling of Amino-Tethered Vinyl Halides with Ketones, Esters, and Nitriles Using Potassium Phenoxide as the Base
✍ Scribed by Daniel Solé; Xavier Urbaneja; Josep Bonjoch
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 151 KB
- Volume
- 346
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
Vinyl halides undergo intramolecular coupling with amino‐tethered ketones, esters, and nitriles in the presence of a palladium catalyst and potassium phenoxide as the base. This reaction constitutes a useful methodology for the synthesis of monocyclic, bridged, and spirocyclic nitrogen‐containing compounds.