✦ LIBER ✦

Palladium-catalyzed intramolecular allylic alkylation of α-sulfinyl carbanions: a new asymmetric route to enantiopure γ-lactams

✍ Scribed by Sophie Vogel; Xavier Bantreil; Guillaume Maitro; Guillaume Prestat; David Madec; Giovanni Poli

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 484 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.01.012

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Phosphine-Free Palladium-Catalyzed Allen

Phosphine-Free Palladium-Catalyzed Allene Carbopalladation/Allylic Alkylation Domino Sequence: A New Route to 4-(α-Styryl) γ-Lactams

✍ Claire Kammerer; Guillaume Prestat; David Madec; Giovanni Poli 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB 👁 1 views

## Abstract **Free to decide**: Various 4‐(α‐styryl) γ‐lactams are synthesized in 61–88 % yield by a phosphine‐free palladium‐catalyzed carbopalladation/allylic alkylation domino sequence (see scheme). The cyclization is totally regio‐ and diastereoselective in favor of the 3,4‐__trans__‐disubstitu

ChemInform Abstract: Phosphine-Free Pall

ChemInform Abstract: Phosphine-Free Palladium-Catalyzed Allene Carbopalladation/Allylic Alkylation Domino Sequence: A New Route to 4-(α-Styryl) γ-Lactams.

✍ Claire Kammerer; Guillaume Prestat; David Madec; Giovanni Poli 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 23 KB 👁 1 views