Palladium catalyzed hydroamination of conjugated enynes
β Scribed by Ukkiramapandian Radhakrishnan; Mohammad Al-Masum; Yoshinori Yamamoto
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 191 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The [(~3-C3Hs)PdCI]2-dppf-AcOH catalytic system effected the hydroamination of conjugated enynes I leading to the formation of (E)-isomer of alkenic 1,4-diamines in stereoselective fashion.
π SIMILAR VOLUMES
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Palladium catalyzed addition of certain carbon pronucleophiles 2 to conjugated enynes l afforded the corresponding allenes 3 in good to excellent yields. The most reactive methynes such o.~ methylmalononitrile 2e enabled to undezgo double addition leading to alkenes 4. Catalyst optimization supporte