Palladium-Catalyzed Formation of Diaryl Ethers from Aryl Bromides. Electron Poor Phosphines enhance Reaction Yields

✍ Scribed by Grace Mann; John F. Hartwig

• Book ID: 104258255
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 517 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10175-7

✦ Synopsis

Aryl bromides were converted to diaryl ethers with sodium aryl oxides in the presence of catslytic amounts of Pd(DBA)2 and DPPF. Isolated yields of over 90% were achievedin reactions with electrondeficientaryl bromidesand electronrich sodiumsryl oxides. EIectronpoorDPPFderivativesled to increasedreactionyields. @ 1997Elsevier science Ltd.