A new approach to the synthesis of funct
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Ahmed Abouabdellah; Robert H. Dodd
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Article
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1998
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Elsevier Science
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French
⚖ 238 KB
The enolate of 4-N-(tert-butyloxycarbonyl)aminobutyro-7-lacto~e 9 reacted with 2-bromo-1methylindole-3-carboxaldehyde it, the presence of stannic chloride to give the product of aldol condensation 16. Deprotection and dehydration of the latter with trifluoroacetic' acid and dimethyl sulfide followed