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Palladium catalyzed cyclization-carbonylation of allylic 2-alkynoates: Facile synthesis of α-alkylidene-γ-butyrolactone β-acetic acid derivatives

✍ Scribed by Jianguo Ji; Xiyan Lu


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
735 KB
Volume
50
Category
Article
ISSN
0040-4020

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13, y-disubstituted (x-alkylidene-y-butyrolactones with cis or trans relative configurations were synthesized in both optically active forms from readily available homochiral allylic 2-alkynoates by Pd(II) catalysis in the presence of CuX2 and LiX Synthesis of homochiral compounds as candidates for