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Palladium-Catalyzed Cross-Coupling Reaction of Secondary Benzylic Bromides with Grignard Reagents

✍ Scribed by López-Pérez, Ana; Adrio, Javier; Carretero, Juan C.


Book ID
120011927
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
288 KB
Volume
11
Category
Article
ISSN
1523-7060

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Silver-catalyzed cross-coupling reaction
✍ Hidenori Someya; Hideki Yorimitsu; Koichiro Oshima 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 958 KB

Treatment of secondary or tertiary alkyl bromides with alkyl Grignard reagents in the presence of catalytic amounts of silver bromide and potassium fluoride in CH 2 Cl 2 afforded the corresponding cross-coupling products in reasonable yields. Moreover, silver showed catalytic activity for the cross-