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Palladium-catalyzed cross-coupling reaction of homoallylic or homopropargylic organozincs with alkenyl halides as a new selective route to 1,5-dienes and 1,5-enynes

โœ Scribed by Negishi, Eiichi; Valente, Louis F.; Kobayashi, Makoto


Book ID
121326129
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
287 KB
Volume
102
Category
Article
ISSN
0002-7863

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The reaction of 9-alkyl-9-BBNs with 1-bromo-i-phenylthioethene or (E)-and (Z)-2-bromo-lphenylthio-1-alkenes takes place readily in the presence of Pd(PPh& and sodium hydroxide to afford stereodefmed vinylic sulfides in excellent yields.