Palladium-catalyzed cross-coupling of pyrrolyl anions with organic halides
โ Scribed by Lucio Filippini; Marilena Gusmeroli; Raul Riva
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 150 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Ambident pyrrolyl anions react with aromatic halides, as well as perfluoroelkyl iodides, in the presence of a palladium catalyst.
๐ SIMILAR VOLUMES
1-Methyl-2-pyrrolyl-magnesium bromide and -zinc chloride, which were prepared from I-methyl-Z-pyrrolyllithium with MgBr2 and ZnC12 respectively, reacted with aryl-and heteroaromatic halides to give the corresponding 2-substituted pyrroles in good to excellent yields in the presence of palladium-phos
The polymer-bound palladium-catalyzed cross-coupling reaction of electrophiles(i.e., halides and triflates) with organoboron compounds to form carbon-carbon bonds was achieved at mild conditions with very high activity in the Suzuki coupling reaction. The polymeric catalyst can be easily separated f