Palladium catalyzed cross-coupling between phenyl- or naphthylboronic acids and benzylic bromides

✍ Scribed by Sultan Chowdhury; Paris E. Georghiou

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 235 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01566-x

✦ Synopsis

The Suzuki-Miyaura palladium-catalyzed coupling reaction was extended to achieve mixed cross-coupling between substituted aryl and naphthyl mono-and bisbromomethanes with phenylboronic acid, l-methoxy-2naphthyl-, 3-methoxy-2-naphthyl-, or 4-methoxy-l-naphthylboronic acid to form the corresponding disubstituted methanes.