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Palladium-Catalyzed Asymmetric Hydrogenation of Simple Ketimines Using a Brønsted Acid as Activator

✍ Scribed by Xiao-Yu Zhou; Ming Bao; Yong-Gui Zhou

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
208 KB
Volume
353
Category
Article
ISSN
1615-4150

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✦ Synopsis

Using a catalytic amount of a Brønsted acid as activator of simple imines, the highly enantioselective homogeneous palladium-catalyzed asymmetric hydrogenation of simple ketimines was successfully developed with up to 95% ee.

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