✦ LIBER ✦
Palladium-catalyzed allylation of lithium 3-alkenyl-1-cyclopentenolates-triethylborane and its application to a selective synthesis of methyl (z)-jasmonate1
✍ Scribed by Fen-Tair Luo; Ei-ichi Negishi
- Book ID
- 104229107
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 280 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A Pd-catalyzed allylation of 3-substituted 1-cyclopentenolates with readily obtainable and storable v-monosubstituted (Z)-allylic acetates in a 1:l ratio in the presence of 2 mol % of Pd(PPh3)4 featuring high yields and high stereo-and regioselectivities has been developed and applied to the synthesis of methyl (z)-jasmonate. The reaction of a 2:l mixture of BEt3 and a lithium 3-alkenyl-1-cyclopentenolate (l),