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Palladium-Catalyzed Alkylation of Vinyl Oxiranes with Substituted Allenes. Direct Access to Bifunctionalized Allylic Alcohols.

✍ Scribed by Perli Nanayakkara; Howard Alper


Book ID
101966649
Publisher
John Wiley and Sons
Year
2004
Weight
26 KB
Volume
35
Category
Article
ISSN
0931-7597

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Regio- and stereoselective palladium(0)-
✍ Maryse Rychlet Elliott; Anne-Lise Dhimane; Max Malacria πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 230 KB

Recently, we reported an efficient palladium(0) catalyzed allylation of a non-stabilized nucleophile, lithium enolate of ethyl isobutyrate 2a, with monoepoxide of isoprene la, as a first step in the total synthesis of epiilludol (scheme 1).] The synthetic value of the regio-and stereoselective allyl