๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Palladium-catalyzed acylation of a 1,2-disubstituted 3-indolylzinc chloride

โœ Scribed by Margaret M. Faul; Leonard L. Winneroski

Book ID
104257386
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
192 KB
Volume
38
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

3-Acylindoles were prepared by palladium catalyzed coupling of an acid sensitive 1,2disubstituted 3-indolylzinc chloride with a number of acid chlorides to give the corresponding ketones in 33-74% yields.

๐Ÿ“œ SIMILAR VOLUMES

Palladium-catalyzed heteroarylation of 1
Palladium-catalyzed heteroarylation of 1-(tert-butyldimethylsilyl)-3-indolylzinc chloride. Efficient synthesis of 3-(2-pyridyl)indoles
โœ Mercedes Amat; Sabine Hadida; Joan Bosch ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 274 KB

Absfruck Palladium-catalyzed coupling of I-(rurr-hulyIdirnrthyl.\ilyl)-3-indolylzinc chloride (2) with either xdeficient or x-excedent heteroaryl halides gives krylindcdcs in good to excellenl yields. The method is extensively applied to !he preparation of J-(2-Fyridyl)indoles.