Palladium-Catalyzed 2,2,2-Trifluoroethylation of Organoboronic Acids and Esters
✍ Scribed by Yanchuan Zhao; Prof. Dr. Jinbo Hu
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 381 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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A lipase-catalyzed enantioselective hydrolysis process under continuous in situ racemization of substrate by using trioctylamine as an organic base was developed for the production of (S)-naproxen from racemic naproxen thioesters in isooctane. Naproxen 2,2,2trifluoroethyl thioester and 45°C were sel