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PAK promotes morphological changes by acting upstream of Rac

✍ Scribed by Obermeier, A.


Book ID
111745554
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
526 KB
Volume
17
Category
Article
ISSN
0261-4189

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Cyclic AMP induces morphological changes
✍ StΓ©phane Pelletier; Catherine Julien; Michel R. Popoff; Nathalie Lamarche-Vane; πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 724 KB

## Abstract Cyclic AMP (cAMP) is a pleiotropic second messenger that regulates numerous cellular processes. In vascular smooth muscle cells (VSMCs), these include cell proliferation, migration, and contractility. Here we show that cAMP‐elevating agents induce dramatic morphological changes in VSMCs