Pairwise linkage disequilibrium analysis of the human renin gene
โ Scribed by Danish Saleheen; Philippe M. Frossard
- Book ID
- 117601721
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 61 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0895-7061
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Haplotypes of the insulin receptor gene were resolved in parents from Scandinavian nuclear families by studying the segregation of seven restriction fragment length polymorphisms (RFLPs). Of 97 unrelated parents, 41 had non-insulin-dependent diabetes mellitus (NIDDM). Considerable linkage disequilib
Although essential arterial hypertension is believed to have a strong genetic predisposition, the gene(s) responsible are unknown. The mechanisms underlying the regulation of blood pressure and experimental studies place the renin gene among the main candidate genes that need to be tested in humans.