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Paired donor interchange to avoid ABO-incompatible living donor liver transplantation

✍ Scribed by See Ching Chan; Chung Mau Lo; Boon Hun Yong; Wilson J. C. Tsui; Kelvin K. C. Ng; Sheung Tat Fan

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 76 KB
Volume: 16
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21970

No coin nor oath required. For personal study only.

✦ Synopsis

We report an emergency paired donor interchange living donor liver transplant performed on January 13, 2009. The 4 operations (2 liver transplants) were performed simultaneously. The aim was to avoid 2 ABO-incompatible liver transplants. One recipient in acute liver failure underwent transplantation in a high-urgency situation. The abdomen of the other recipient had severe adhesions from previous spontaneous bacterial peritonitis that rendered the recipient operation almost impossible. The ethical and logistical issues are discussed. Approaches adopted in anticipation of potential adverse outcomes are explained in view of the higher donor and recipient mortality and morbidity rates in comparison with kidney transplantation.

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