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Pain and emotion in the insular cortex: evidence for functional reorganization in major depression

✍ Scribed by Isabella Mutschler; Tonio Ball; Johanna Wankerl; Irina A. Strigo

Book ID: 116774087
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 370 KB
Volume: 520
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2012.03.095

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## Background: Signal hyperintensities on magnetic resonance imaging in late-life depression are associated with treatment resistance and poor outcome. these lesions are probably vascular in origin and proposed sites for vascular damage include the dorsolateral prefrontal cortex (dlpfc) and anterio