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Pain and dyskinesia in Parkinson's disease

✍ Scribed by Carlos Juri; Maria C. Rodríguez-Oroz; Juan A. Burguera; Jorge Guridi; Jose A. Obeso

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
178 KB
Volume
25
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Lerner and Bagic 1 have to be congratulated for their hypothesis on PD pathogenesis. They suggest that the sequence of the brain changes in PD follows specific and repeatable patterns in all cases, as well as that a prion-like process underlies neurodegeneration. These ideas could explain several features of PD, such as the high prevalence of olfactory, autonomic, or sleep abnormalities. However, any pathogenic hypothesis should also explain: *TEMPO, Rasagiline Mesylate [TVP-1012] in Early Monotherapy for Parkinson's Disease Outpatients; PRESTO, Parkinson's Rasagiline: Efficacy and Safety in the Treatment of ''Off.''

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