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PAH–DNA adducts in environmentally exposed population in relation to metabolic and DNA repair gene polymorphisms

✍ Scribed by Blanka Binkova; Irena Chvatalova; Zdena Lnenickova; Alena Milcova; Elena Tulupova; Peter B. Farmer; Radim J. Sram

Book ID: 113809024
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 444 KB
Volume: 620
Category: Article
ISSN: 0027-5107
DOI: 10.1016/j.mrfmmm.2007.02.022

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## Abstract To determine whether variations in DNA repair genes are related to host DNA damage, we investigated the association between polymorphism in the __XPD__ gene (codon 199, 312, 751) and the __XRCC1__ gene (codon 194, 399) and the presence of benzo(a)pyrene diolepoxide adducts to lymphocyte