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Paget's disease mimicing skeletal metastases in a patient with coexisting prostatic carcinoma

✍ Scribed by Weih-Jeh Shih; Christine Riley; Sylvia Magoun; U. Yun Ryo

Publisher
Springer
Year
1988
Tongue
English
Weight
883 KB
Volume
14-14
Category
Article
ISSN
0340-6997

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✦ Synopsis

We present a 93-year-old man with prostatic carcinoma whose 99mTc-HMDP skeletal images showed multiple areas of abnormally increased radioactivity in the bone and virtual absence of renal activity. These findings were interpreted as representing multiple skeletal metastases. When correlated with concurrent radiographs, the abnormalities were found to be due to Paget's disease. Multiple areas of bone involvement are not rare in Paget's disease. We reemphasize that an abnormal bone scintigram should always be correlated with regional radiographs to rule out conditions other than malignancy.

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## Abstract Hearing loss in Paget's disease, a metabolic bone disease, has been reported in as many as 60% of cases, and is presumably related to changes in mineral density of the otic capsule. We describe a 59‐year‐old man with Paget's disease who had severe to profound hearing loss and was referr