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Paget's disease and osteoclast biology

✍ Scribed by Roodman, G.D.


Book ID
123090585
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
459 KB
Volume
19
Category
Article
ISSN
8756-3282

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Etiology of Paget's disease and osteocla
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## Abstract Paget's disease of bone is a chronic focal skeletal disorder that affects up to 2–3% of the population over the age of 60 years. Paget's disease is primarily a disease of the osteoclast. The pathologic abnormality in patients with Paget's disease involves increased bone resorption by th

Cell biology of paget's disease
✍ Sakamuri V. Reddy; Cheikh Menaa; Frederick R. Singer; Anne Demulder; G. David Ro πŸ“‚ Article πŸ“… 1999 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 677 KB

## Abstract Paget's disease is characterized by markedly increased osteoclast formation and bone resorption followed by excessive new bone formation. Osteoclasts in Paget's disease are increased both in number and size, contain paramyxoviral‐like nuclear inclusions, and can have up to 100 nuclei pe