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Paclitaxel cytotoxicity is significantly enhanced by a novel pro-apoptotic agent in the treatment of non-small cell lung cancer

✍ Scribed by Syed Shahzad Razi; Koji Park; Xiaogui Li; George Jour; Gary Schwartz; George Todd; Scott Belsley; Cliff P. Connery; Faiz Y. Bhora


Book ID
113680612
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
98 KB
Volume
213
Category
Article
ISSN
1072-7515

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## Abstract In this study, we have characterized a panel of NSCLC cell lines with differential sensitivity to gefitinib for activating mutations in __egfr__, __pik3ca__, and __k‐ras__, and basal protein expression levels of PTEN. The __egfr__ mutant NSCLC cell line H1650 as well as the __egfr__ wil