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PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons

✍ Scribed by Delcourt, Nicolas; Thouvenot, Eric; Chanrion, Benjamin; Galéotti, Nathalie; Jouin, Patrick; Bockaert, Joël; Marin, Philippe

Book ID: 110031984
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 408 KB
Volume: 26
Category: Article
ISSN: 0261-4189
DOI: 10.1038/sj.emboj.7601608

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## Abstract The receptors for insulin and insulin‐like growth factor I (IGF‐I) have in common a high sequence homology and diverse overlapping functions, (e.g., the stimulation of acute metabolic events and the induction of cell growth.). In the present study, we have compared the potential of insu