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P96 Design and one-pot synthesis of α-aminophosphonates and bis(α-aminophosphonates) by iron (III) chloride and cytotoxic activity

✍ Scribed by H. Firouzabadi; M. Jafari; A. Ghaderi; Z. Rezaei

Book ID: 119565520
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 46 KB
Volume: 34
Category: Article
ISSN: 0924-8579
DOI: 10.1016/s0924-8579(09)70315-2

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## Abstract A simple, efficient, and general method has been developed for the one‐pot, three‐component synthesis of α‐aminophosphonates from a condensation reaction of trimethyl phosphite, aldehydes, and amines in the presence of catalytic amount of boric acid (10 mol%) under solvent‐free conditio