p95vav associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-α in megakaryocytic cell lines

Interferon-α-(IFN) producing CHO cell li

Interferon-α-(IFN) producing CHO cell lines are resistant to the antiproliferative activity of IFN: A correlation with gene expression

✍ M. van Heuvel; M. Govaert-Siemerink; I. J. Bosveld; E. G. Zwarthoff; J. Trapman 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 575 KB

CHO cell lines that constitutively produce the murine interferon-alpha (IFN-alpha) subspecies alpha 4 and alpha 6 were constructed. The producer cell lines were protected against viral (vesicular stomatitis virus) infection by the IFN species secreted, but were resistant to the growth inhibitory act