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P833 - DQA1 and DQB1 promoter polymorphisms in autoimmunity

✍ Scribed by Burkhard J Manfras; Schneider Susanne; Böttcher Annette; Löliger Cornelius; Kühnl Peter; Bernhard O Boehm

Book ID: 116115239
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 180 KB
Volume: 47
Category: Article
ISSN: 0198-8859
DOI: 10.1016/0198-8859(96)85528-5

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We have investigated the DNA polymorphism for the DQA1 promoter region (QAP) and HLAclass II DRB1, DQA1, and DQB1 genes in 178 central European patients with Systemic lupus erythematosus (SLE) using polymerase chain reaction and Dig-ddUTP labeled oligonucleotides. Increased frequencies of DRBl\*02 a