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P76 SUBCHONDRAL BONE CHANGE IS SECONDARY TO CARTILAGE DEGENERATION IN THE RAT MENISCECTOMY MODEL OF OSTEOARTHRITIS

✍ Scribed by H. Yasui; J. Hata; K. Yamana; H. Takagi; T. Jinbo; T. Shimomoto; D. Miura; Y. Harada; Y. Oue; Y. Azuma

Book ID: 114349423
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 38 KB
Volume: 14
Category: Article
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(07)60528-7

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## Objective: It has been suggested that subchondral bone remodeling plays a role in the progression of osteoarthritis (oa). to test this hypothesis, we characterized the changes in the rat anterior cruciate ligament transection (aclt) model of oa and evaluated the effects of alendronate (aln), a p