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p73 is dispensable for commitment to neural stem cell fate, but is essential for neural stem cell maintenance and for blocking premature differentiation

✍ Scribed by Alexandrova, E M; Talos, F; Moll, U M

Book ID: 120287899
Publisher: Nature Publishing Group
Year: 2012
Tongue: English
Weight: 74 KB
Volume: 20
Category: Article
ISSN: 1350-9047
DOI: 10.1038/cdd.2012.134

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## Abstract The aim of our study was to investigate whether a human neural cell line could be used as a reliable screening tool to examine the functional conservation, in humans, of transcription factors involved in neuronal or glial specification in other species. Gain‐of‐function experiments were