P7 peptides suppress the proliferation of K562 cells induced by basic fibroblast growth factor
β Scribed by Wang, Cong; Yu, Yonglin; Li, Quchou; Gao, Susu; Jia, Xinglong; Chen, Xilei; Wang, Ruixue; Li, Tao; Wang, Wenhui; Li, Xiaokun; Wu, Xiaoping
- Book ID
- 118302741
- Publisher
- S. Karger AG
- Year
- 2012
- Tongue
- English
- Weight
- 486 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1010-4283
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AR4-2J, a rat pancreatic acinar-tumor cell line, was used to investigate long-term effects of basic fibroblast growth factor (bFGF) and somatostatin on pancreatic cancer cells. We observed that bFGF stimulated cell proliferation when cells were cultured in serum-free medium. The effect was dose-depe
## Abstract Basic fibroblast growth factor (bFGF) is produced by bone marrow stromal cells as well as by normal and leukemic hematopoietic cells. In this study, we examine the direct effects of bFGF on erythroid differentiation in K562 cells in order to determine whether bFGF can promote the expres