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p66/p51 and p51/p51 recombinant forms of reverse transcriptase from human immunodeficiency virus type 1 : Interactions with primer tRNALys3, initiation of cDNA synthesis, and effect of inhibitors

✍ Scribed by Emmanuelle Dufour; Rim El Dirani-Diab; Florence Boulmé; Michel Fournier; Georgyi Nevinsky; Laura Tarrago-Litvak; Simon Litvak; Marie-Line Andreola

Book ID
114428901
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
470 KB
Volume
251
Category
Article
ISSN
1432-1327

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## Abstract The p66/p51 human immunodeficiency virus type 1 reverse transcriptase is a heterodimer with identical N‐terminal amino acid sequences. The enzyme contains two polymerization domains and one RNase H domain, which is located at the C‐terminus of the p66 subunit. Both polymerization domain