## Abstract Primary cultures of human hepatocytes and hepatoma cell line HepG2 are frequently used to evaluate the hepatic disposition of drugs and other xenobiotics. To check the variability of the expression of drug‐metabolizing enzymes in these in vitro models, expression of genes coding for sev
✦ LIBER ✦
P60 The effect of longer time culture and delayed primary cell divisions on the rate of self-correction in human blastocysts
✍ Scribed by H. Gourabi; M. Bazrgar; P. Eftekhari-Yazdi; H. Vaziri; M. Fakhri; F. Hassani; M.R. Rezazadeh Valojerdi
- Book ID
- 119612873
- Publisher
- Reproductive Healthcare Ltd
- Year
- 2012
- Tongue
- English
- Weight
- 44 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1472-6491
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The influence of cell density and epidermal growth factor (EGF) on the expression and inducibility of cytochrome P450 (CYP) genes of the CYP3A and CYP1A families in adult human hepatocytes in primary culture has been evaluated. Only when cultured at subconfluence and in the presence of EGF did hepat