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p56chk1 protein kinase is required for the DNA replication checkpoint at 37C in fission yeast

✍ Scribed by Francesconi, S.


Book ID
111745277
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
591 KB
Volume
16
Category
Article
ISSN
0261-4189

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) Ξ΄ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCΞ΄ has a negative effect on cell proliferation. However, the mode of PKCΞ΄ activation, the cell cycle stage requ