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P5.64 Effect of morbid obesity in skeletal muscle and its association with insulin resistance

✍ Scribed by A.R. Silvestre; M. Machado; L. Vilarinho; H. Cortez-Pinto; T. Evangelista

Book ID
116794906
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
49 KB
Volume
21
Category
Article
ISSN
0960-8966

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## Abstract Protein kinase C ΞΈ (PKC‐θ) is the PKC isoform predominantly expressed in skeletal muscle, and it is supposed to mediate many signals necessary for muscle histogenesis and homeostasis, such as TGFΞ², nerve‐dependent signals and insulin. To study the role of PKC‐θ in these mechanisms we ge