p53 Mutations are present in colorectal
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Agneta Jansson; Massimiliano Gentile; Xiao-Feng Sun
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Article
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2001
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John Wiley and Sons
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French
⚖ 401 KB
Previous studies have shown that nuclear p53 over-expression is an indicator of p53 mutations whereas cytoplasmic p53 accumulation is related to wild-type p53 in several kinds of tumors. Cytoplasmic p53 accumulation has been demonstrated to be an independent prognostic factor in colorectal adenocarc